Primaquine revisited six decades after its discovery
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Primaquine revisited six decades after its discovery.
Primaquine was firstly synthesized in 1946 in the USA, and is the most representative member of the anti-malarial 8-aminoquinolines. Six decades have passed and primaquine is still the only transmission-blocking anti-malarial clinically available, displaying a marked activity against gametocytes of all species of human malaria, including multi-resistant Plasmodium falciparum strains. Primaquine...
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ژورنال
عنوان ژورنال: European Journal of Medicinal Chemistry
سال: 2009
ISSN: 0223-5234
DOI: 10.1016/j.ejmech.2008.08.011